Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | WHR1 | P49842 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12970528 | 0.79 | FYN (0.48) | ALDH1A1GAAKMT2A | |
| SCHEMBL26739765 | 0.78 | FLT1 (0.44) | CTDSP1ALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL20657559 | 0.78 | KMT2A (0.39) | ALDH1A1SMN1; SMN2GAAMAPTADORA1 | |
| SCHEMBL2479064 | 0.77 | PDE10A (0.48) | ALDH1A1SMN1; SMN2L3MBTL1MAPTPDGFRB | |
| SCHEMBL2042584 | 0.77 | FFAR2 (0.51) | PDGFRBPDGFRAKMT2AHSP90AA1 | |
| SCHEMBL27070678 | 0.76 | ACHE (0.38) | ALDH1A1SMN1; SMN2GAAL3MBTL1MAPT | |
| SCHEMBL22446544 | 0.76 | PDGFRB (0.43) | CTDSP1ALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL10205830 | 0.76 | KMT2A (0.53) | ALDH1A1SMN1; SMN2L3MBTL1ADORA1KMT2A | |
| SCHEMBL29739398 | 0.74 | MAPT (0.51) | ALDH1A1L3MBTL1MAPTPDGFRBPDGFRA | |
| SCHEMBL28501584 | 0.74 | FFAR2 (0.49) | ALDH1A1SMN1; SMN2GAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428720-A1 | OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE. | MERCK PATENT GMBH (DE) | 1991-05-29 | — | — | EP | disclosed |
| WO-1990013611-A2 | OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-11-15 | — | — | WO | disclosed |