Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.72 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16887915 | 0.98 | OPRM1 (0.70) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL3408220 | 0.84 | OPRM1 (1.00) | OPRM1OPRL1OPRK1 | |
| SCHEMBL16887903 | 0.81 | OPRM1 (0.49) | OPRM1OPRL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5310264 | 0.80 | OPRM1 (0.54) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL16887907 | 0.78 | OPRM1 (0.54) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL27075238 | 0.78 | OPRM1 (0.55) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL3408053 | 0.75 | OPRL1 (1.00) | OPRM1OPRL1OPRK1 | |
| SCHEMBL8605980 | 0.75 | OPRM1 (0.59) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL16887904 | 0.75 | OPRM1 (0.48) | OPRM1OPRL1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5308781 | 0.74 | OPRM1 (0.57) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994465-A | Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0384320-A1 | Antihyperlipidemic and anti-atherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |