Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.63 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263972 | 0.84 | SOAT1 (0.69) | SOAT1SOAT2PPARGPPARA | |
| SCHEMBL10587594 | 0.84 | SOAT1 (0.69) | SOAT1SOAT2PPARGPPARA | |
| SCHEMBL9152529 | 0.82 | SOAT1 (0.67) | SOAT1SOAT2PPARGPPARAPPARD | |
| SCHEMBL9257327 | 0.81 | SOAT1 (0.86) | SOAT1SOAT2PPARGPPARAPPARD | |
| SCHEMBL10587602 | 0.81 | SOAT1 (0.86) | SOAT1SOAT2PPARGPPARAPPARD | |
| SCHEMBL9195286 | 0.81 | ULK1 (0.53) | SOAT1 | |
| SCHEMBL9157883 | 0.81 | SOAT1 (0.66) | SOAT1SOAT2PPARGPPARAPPARD | |
| SCHEMBL9256286 | 0.81 | SOAT1 (0.74) | SOAT1SOAT2PPARGPPARAPPARD | |
| SCHEMBL9252473 | 0.81 | SOAT1 (0.74) | SOAT1SOAT2PPARGPPARAPPARD | |
| SCHEMBL10891868 | 0.80 | SOAT1 (0.70) | SOAT1SOAT2PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384320-A1 | Antihyperlipidemic and anti-atherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | claimed |
| US-4994465-A | Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0384320-A1 | Antihyperlipidemic and anti-atherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |