SCHEMBL9765090

SCHEMBL9765090

CCc1nc(N)nc(N)c1-c1cccc([N+](=O)[O-])c1NC

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.53
NCOA3 Q9Y6Q9 1/20 0.53
CYP2D6 P10635 1/20 0.53
HEXA P06865 1/20 0.51
HEXB P07686 1/20 0.51
REN P00797 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9765076 0.85 HEXA (0.62) NCOA1NCOA3CYP2D6HEXAHEXB
Water SCHEMBL9765099 0.84 HEXA (0.60) NCOA1NCOA3CYP2D6HEXAHEXB
SCHEMBL8588709 0.74 CYP2D6 (0.77) NCOA1NCOA3CYP2D6
SCHEMBL9765082 0.71 HEXA (0.64) NCOA1NCOA3CYP2D6HEXAHEXB
SCHEMBL6049489 0.71 HEXA (0.62) NCOA1NCOA3CYP2D6HEXAHEXB
Water SCHEMBL9765101 0.70 HEXA (0.62) NCOA1NCOA3CYP2D6HEXAHEXB
SCHEMBL6244594 0.70 GHSR (0.76) NCOA1NCOA3CYP2D6HEXAHEXB
SCHEMBL6359292 0.69 NCOA1 (1.00) NCOA1NCOA3CYP2D6
SCHEMBL9485616 0.69 CYP2D6 (0.82) NCOA1NCOA3CYP2D6
SCHEMBL12368255 0.69 HEXA (1.00) CYP2D6HEXAHEXBREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4992444-A Antitumor agents, skin disorders BRITISH TECHNOLOGY GROUP LIMITED (GB) 1991-02-12 US claimed