Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 1.00 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903770 | 0.84 | NCOA1 (0.71) | NCOA1NCOA3CYP2D6 | |
| SCHEMBL9485648 | 0.84 | NCOA1 (0.72) | NCOA1NCOA3CYP2D6 | |
| SCHEMBL8591506 | 0.83 | NCOA1 (0.71) | NCOA1NCOA3CYP2D6 | |
| SCHEMBL11002112 | 0.83 | NCOA1 (0.71) | NCOA1NCOA3CYP2D6 | |
| SCHEMBL8588709 | 0.83 | CYP2D6 (0.77) | NCOA1NCOA3CYP2D6 | |
| SCHEMBL30966673 | 0.83 | NCOA1 (0.70) | NCOA1NCOA3CYP2D6 | |
| SCHEMBL6051207 | 0.83 | NCOA1 (0.70) | NCOA1NCOA3CYP2D6 | |
| SCHEMBL3059317 | 0.83 | NCOA1 (0.70) | NCOA1NCOA3CYP2D6 | |
| SCHEMBL9485926 | 0.82 | NCOA1 (0.70) | NCOA1NCOA3CYP2D6 | |
| SCHEMBL9485616 | 0.82 | CYP2D6 (0.82) | NCOA1NCOA3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001509149-A | — | — | 2001-07-10 | — | — | JP | claimed |
| EP-0961772-A1 | 2,4-DIAMINOPYRIMIDINE COMPOUNDS AS ANTI-CANCER AGENTS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1999-12-08 | — | — | EP | claimed |
| WO-1998030550-A1 | 2,4-DIAMINOPYRIMIDINE COMPOUNDS AS ANTI-CANCER AGENTS | BTG INTERNATIONAL LIMITED (GB) | 1998-07-16 | — | — | WO | claimed |
| WO-2023081141-A1 | THYMIDYLATE SYNTHASE INHIBITORS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-05-11 | — | — | WO | disclosed |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | KOSOGOF CHRISTI (US) | 2005-08-04 | — | — | US | disclosed |
| US-5627189-A | Insecticidal 5-substituted-2,4-diaminopyrimidine derivatives | FMC CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| US-5618928-A | USEFUL IN TREATMENT OF PNEUMOCYSTIS CARINII INFECTIONS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-5587379-A | CONTROLLING INSECTS IN AGRICULTURAL CROPS | FMC CORPORATION (US) | 1996-12-24 | — | — | US | disclosed |
| US-5521192-A | TOBACCO BUDWORM, CABBAGE LOOPER, BEET ARMYWORM | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| EP-0671881-A4 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES. | FMC CORP (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0671881-A1 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES | FMC CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994012032-A1 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES | FMC CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |
| EP-0290558-B1 | ANTIFOLATE AGENTS | BTG INTERNATIONAL LIMITED (GB) | 1993-06-16 | — | — | EP | disclosed |
| US-4992444-A | Antitumor agents, skin disorders | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0290558-A1 | ANTIFOLATE AGENTS. | STEVENS MALCOLM FRANCIS GRAHAM (GB) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988004293-A1 | ANTIFOLATE AGENTS | STEVENS MALCOLM FRANCIS GRAHAM (GB) | 1988-06-16 | — | — | WO | disclosed |
| EP-0147443-A1 | PYRIMIDINE DERIVATIVES | Aston Molecules Limited (GB) | 1985-07-10 | — | — | EP | disclosed |
| WO-1984004746-A1 | PYRIMIDINE DERIVATIVES | UNIV BIRMINGHAM (GB) | 1984-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | GHSR, GIPR, GPR119 | NCOA1 1701/4885NCOA3 2738/4885CYP2D6 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.