Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.65 |
| ▸ | HTR1B | P28222 | 6/20 | 0.65 |
| ▸ | HTR1A | P08908 | 4/20 | 0.65 |
| ▸ | HTR2A | P28223 | 3/20 | 0.65 |
| ▸ | HTR2B | P41595 | 2/20 | 0.65 |
| ▸ | HTR7 | P34969 | 2/20 | 0.65 |
| ▸ | HTR5A | P47898 | 2/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | HTR1E | P28566 | 1/20 | 0.65 |
| ▸ | HTR1F | P30939 | 1/20 | 0.65 |
| ▸ | HTR3A | P46098 | 1/20 | 0.65 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800416 | 0.88 | HTR1B (0.54) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL9765120 | 0.87 | HTR1D (0.68) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| Succinic Acid SCHEMBL5334862 | 0.84 | HTR1D (0.62) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| Dimethylamine SCHEMBL8927414 | 0.84 | HTR1D (0.71) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL8092644 | 0.84 | HTR1D (0.74) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL10494722 | 0.83 | HTR1D (0.67) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| Sumatriptan SCHEMBL6689001 | 0.83 | HTR1A (0.87) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| Sumatriptan SCHEMBL2404748 | 0.82 | HTR1A (0.85) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| Sumatriptan SCHEMBL41674 | 0.82 | HTR1A (0.85) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| Sumatriptan SCHEMBL1556482 | 0.82 | HTR1A (0.85) | HTR1DHTR1BHTR1AHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037845-A | Analgesics; for treatment or prevention of pain due to vasodilation in the cranium | GLAXO GROUP LIMITED (GB) | 1991-08-06 | — | — | US | disclosed |