Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 9/20 | 0.54 |
| ▸ | HTR1D | P28221 | 8/20 | 0.54 |
| ▸ | HTR1A | P08908 | 7/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | HTR5A | P47898 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | HTR1E | P28566 | 1/20 | 0.54 |
| ▸ | HTR1F | P30939 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765109 | 0.88 | HTR1D (0.65) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800358 | 0.87 | HTR1D (0.56) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800384 | 0.85 | HTR1D (0.59) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800380 | 0.85 | HTR1D (0.53) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800378 | 0.85 | HTR1A (0.48) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| Oxalic Acid SCHEMBL9800389 | 0.83 | HTR1A (0.72) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800332 | 0.83 | HTR1A (0.59) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800335 | 0.83 | HTR1A (0.61) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800430 | 0.83 | MTNR1A (0.60) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800344 | 0.83 | MTNR1A (0.62) | HTR1BHTR1DHTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994483-A | 5-substituted-3-aminoalkyl indole derivatives for migraine | GLAXO GROUP LIMITED (GB) | 1991-02-19 | — | — | US | disclosed |
| CN-85104233-A | Chemical compound | — | 1987-01-07 | — | — | CN | disclosed |