Ethylene Glycol

Ethylene Glycol

SCHEMBL9765110

C=C(C)C(=O)OCCCCOC(=O)C(=C)C.C=CC.OCCO

nearest known ligand 0.61

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.61
THRB P10828 1/20 0.48
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.37
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
ACHE P22303 6/20 0.32
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL28204235 0.92 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
Ethylene Glycol SCHEMBL8852703 0.92 THRB (0.57) TSHRTHRBPOLBAPEX1HTT
Ethylene Glycol SCHEMBL10718145 0.92 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
Ethylene Glycol SCHEMBL42531 0.92 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
Ethylene Glycol SCHEMBL3867476 0.90 TSHR (0.74) TSHRTHRBPOLBAPEX1HTT
Propene SCHEMBL10530371 0.88 THRB (0.52) TSHRTHRBPOLBAPEX1HTT
Propene SCHEMBL998377 0.88 THRB (0.52) TSHRTHRBPOLBAPEX1HTT
Propene SCHEMBL4957928 0.88 THRB (0.52) TSHRTHRBPOLBAPEX1HTT
Propene SCHEMBL6739183 0.88 THRB (0.52) TSHRTHRBPOLBAPEX1HTT
Propene SCHEMBL10531728 0.88 THRB (0.52) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5001203-A UV curable polyorganophosphazene composition ETHYL CORPORATION (US) 1991-03-19 US disclosed
EP-0334090-A2 Acrylate cured polyphosphazenes ETHYL CORPORATION (US) 1989-09-27 EP disclosed