Propene

Propene

SCHEMBL998377

C=C(C)C(=O)OCCO.C=CC.C=CC

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.52
TSHR P16473 8/20 0.50
ALDH1A1 P00352 5/20 0.40
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
ACHE P22303 1/20 0.32
HPGD P15428 1/20 0.31
TP53 P04637 2/20 0.30
HIF1A Q16665 2/20 0.30
CYP3A4 P08684 1/20 0.30
HSD17B10 Q99714 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL10531877 1.00 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Propene SCHEMBL10530384 1.00 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Propene SCHEMBL4957928 1.00 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Propene SCHEMBL10531728 1.00 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Propene SCHEMBL10530371 1.00 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Propene SCHEMBL628378 1.00 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Propene SCHEMBL10531739 1.00 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Propene SCHEMBL6739183 1.00 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Ethylene Glycol SCHEMBL8852703 0.92 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9515117 0.92 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12036312-B2 Non-aqueous topical compositions comprising a halogenated salicylanilide UNION therapeutics A/S (DK) 2024-07-16 US claimed
CN-112313577-B Radiation curable composition for additive manufacturing 斯特拉塔西斯公司 2024-07-09 CN claimed
US-20230407132-A1 (METH)ACRYLATE-FUNCTIONAL RADIATION CURABLE COMPOSITIONS FOR ADDITIVE FABRICATION COVESTRO (NETHERLANDS) B.V. (NL) 2023-12-21 US claimed
EP-4237175-A1 (METH)ACRYLATE-FUNCTIONAL RADIATION CURABLE COMPOSITIONS FOR ADDITIVE FABRICATION Covestro (Netherlands) B.V. (NL) 2023-09-06 EP claimed
US-11485818-B2 Radiation curable compositions for additive fabrication COVESTRO (NETHERLANDS) B.V. (NL) 2022-11-01 US claimed
WO-2022090342-A1 (METH)ACRYLATE-FUNCTIONAL RADIATION CURABLE COMPOSITIONS FOR ADDITIVE FABRICATION COVESTRO (NETHERLANDS) BV (NL) 2022-05-05 WO claimed
US-20210238339-A1 RADIATION CURABLE COMPOSITIONS FOR ADDITIVE FABRICATION STRATASYS INC. 2021-08-05 US claimed
EP-3781987-A1 RADIATION CURABLE COMPOSITIONS FOR ADDITIVE FABRICATION DSM IP Assets B.V. (NL) 2021-02-24 EP claimed
CN-112313577-A Radiation curable compositions for additive manufacturing 帝斯曼知识产权资产管理有限公司 2021-02-02 CN claimed
EP-3429691-B1 NON-AQUEOUS TOPICAL COMPOSITIONS COMPRISING A HALOGENATED SALICYLANILIDE UNION THERAPEUTICS AS (DK) 2020-11-04 EP claimed
US-7906564-B2 Self etch all purpose dental cement composition, method of manufacture, and method of use thereof PENTRON CLINICAL TECHNOLOGIES, LLC (US) 2011-03-15 US claimed
CN-101720239-A Implant device release agent and method of use thereof ENDO PHARMACEUTICALS SOLUTIONS 2010-06-02 CN claimed
EP-2139533-A2 IMPLANT DEVICE RELEASE AGENTS AND METHODS OF USING SAME Endo Pharmaceuticals Solutions Inc. (US) 2010-01-06 EP claimed
US-20080311170-A1 IMPLANT DEVICE RELEASE AGENTS AND METHODS OF USING SAME INDEVUS PHARMACEUTICALS, INC. 2008-12-18 US claimed
WO-2008134475-A2 IMPLANT DEVICE RELEASE AGENTS AND METHODS OF USING SAME ENDO PHARMACEUTICALS SOLUTIONS INC., 33 (US) 2008-11-06 WO claimed
EP-1986588-A2 SELF ETCH ALL PURPOSE DENTAL COMPOSITION Pentron Clinical Technologies, LLC (US) 2008-11-05 EP claimed
US-20080242761-A1 One part acrylated monomer with aromatic carboxylic anhydride functionality, multifunctional acrylate resin, diluent monomer and curing system; one step restorative dentistry; self and light curable JIA WEITAO 2008-10-02 US claimed
WO-2007100569-A2 SELF ETCH ALL PURPOSE DENTAL COMPOSITION PENTRON CLINICAL TECHNOLOGIES LLC (US) 2007-09-07 WO claimed
US-20070197683-A1 SELF ETCH ALL PURPOSE DENTAL COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF PENTRON CLINICAL TECHNOLOGIES, INC (US) 2007-08-23 US claimed
US-20070197682-A1 Self etch all purpose dental cement composition, method of manufacture, and method of use thereof PENTRON CORPORATION 2007-08-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197682-A1 Self etch all purpose dental cement composition, method of manufacture, and method of use thereof FHIT, COPE, ASH2L THRB 3947/4885TSHR 4848/4885ALDH1A1 4447/4885
US-20080311170-A1 IMPLANT DEVICE RELEASE AGENTS AND METHODS OF USING SAME PTGES, VDR, HPGDS THRB 1368/4885TSHR 476/4885ALDH1A1 4813/4885
US-12036312-B2 Non-aqueous topical compositions comprising a halogenated salicylanilide CUTA, PTPN21, ABL2 THRB 4089/4885TSHR 3500/4885ALDH1A1 1402/4885
US-20070197683-A1 SELF ETCH ALL PURPOSE DENTAL COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF CAD, FHIT, ACR THRB 1851/4885TSHR 4432/4885ALDH1A1 681/4885
US-20080242761-A1 One part acrylated monomer with aromatic carboxylic anhydride functionality, multifunctional acrylate resin, diluent monomer and curing system; one step restorative dentistry; self and light curable CAD, TAS2R42, ACR THRB 1701/4885TSHR 3760/4885ALDH1A1 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.