Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596041 | 0.78 | RAB9A (0.43) | MAPTGAARXFP1RAB9AHTT | |
| SCHEMBL2480481 | 0.74 | GALR3 (0.45) | MAPTGAARXFP1RAB9AHTT | |
| SCHEMBL18525728 | 0.74 | MAPT (0.44) | MAPTGAARXFP1RAB9AHTT | |
| SCHEMBL2685269 | 0.70 | RAB9A (0.49) | MAPTGAARXFP1RAB9AHTT | |
| SCHEMBL31277798 | 0.69 | RAB9A (0.46) | MAPTGAARXFP1RAB9AHTT | |
| SCHEMBL19941773 | 0.69 | RAB9A (0.46) | MAPTGAARXFP1RAB9AHTT | |
| SCHEMBL6078615 | 0.69 | KDM4C (0.40) | MAPTGAARXFP1RAB9AHTT | |
| SCHEMBL11597678 | 0.68 | RAB9A (0.50) | MAPTGAARXFP1RAB9AHTT | |
| SCHEMBL22442908 | 0.67 | HTT (0.42) | MAPTGAARXFP1RAB9AHTT | |
| SCHEMBL766829 | 0.67 | GALR3 (0.49) | MAPTGAARXFP1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009154-B1 | COMPLEXES OF 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITIONS CONTAINING THE COMPLEXES AS ACTIVE INGREDIENTS | Newport Pharmaceuticals International, Inc. (US) | 1982-12-08 | — | — | EP | claimed |
| EP-0009155-B1 | 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITION CONTAINING THE 9-HYDROXYALKYL-PURINES AS ACTIVE INGREDIENTS | Newport Pharmaceuticals International, Inc. (US) | 1982-11-17 | — | — | EP | claimed |
| EP-0009155-A1 | 9-Hydroxyalkyl-purines, processes for preparing them and therapeutical composition containing the 9-hydroxyalkyl-purines as active ingredients | Newport Pharmaceuticals International, Inc. (US) | 1980-04-02 | — | — | EP | claimed |
| EP-0009154-A1 | Complexes of 9-hydroxyalkyl-purines, processes for preparing them and therapeutical compositions containing the complexes as active ingredients | Newport Pharmaceuticals International, Inc. (US) | 1980-04-02 | — | — | EP | claimed |
| EP-0355085-B1 | A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES | CO PHARMA CORPORATION S.R.L. (IT) | 1991-09-11 | — | — | EP | disclosed |