Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSH | P09668 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434405 | 0.93 | GPR35 (0.57) | GPR35TSHRTP53HPGDSMN1; SMN2 | |
| SCHEMBL34473998 | 0.81 | TDP1 (0.47) | GPR35TSHRTP53HPGDSMN1; SMN2 | |
| SCHEMBL6816142 | 0.81 | G6PD (0.51) | GPR35TDP1ALDH1A1L3MBTL1POLB | |
| SCHEMBL218885 | 0.79 | TDP1 (0.63) | GPR35TSHRTP53HPGDSMN1; SMN2 | |
| SCHEMBL7334737 | 0.78 | TDP1 (0.50) | GPR35TSHRTP53HPGDSMN1; SMN2 | |
| SCHEMBL5583106 | 0.78 | TSHR (0.47) | GPR35TSHRTP53HPGDSMN1; SMN2 | |
| SCHEMBL27484289 | 0.78 | GPR35 (0.53) | GPR35TSHRSMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL34473595 | 0.77 | TDP1 (0.47) | GPR35TSHRTP53HPGDSMN1; SMN2 | |
| SCHEMBL4217608 | 0.77 | TDP1 (0.55) | GPR35TSHRTP53HPGDSMN1; SMN2 | |
| SCHEMBL31170798 | 0.77 | TDP1 (0.67) | GPR35TSHRCYP3A4TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041671-A | Process for the preparation 4-chloro-2,5-dimethoxy-aniline | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |