SCHEMBL9765230

SCHEMBL9765230

CCCCS(=O)(=O)NNS(=O)(=O)CCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 2/20 0.41
NPC1 O15118 1/20 0.41
S1PR2 O95136 1/20 0.41
S1PR4 O95977 1/20 0.41
TP53 P04637 1/20 0.41
POLB P06746 1/20 0.41
XBP1 P17861 1/20 0.41
S1PR1 P21453 1/20 0.41
MAPK1 P28482 1/20 0.41
AGTR1 P30556 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10616576 0.95 HPGD (0.44) HPGDALDH1A1MAPTLMNANPC1
SCHEMBL4565920 0.86 FAAH (0.50) HPGDCA1CA2CA12CA7
SCHEMBL10778738 0.85 HPGD (0.38) HPGDALDH1A1MAPTLMNANPC1
SCHEMBL15177331 0.84 HPGD (0.41) HPGDALDH1A1MAPTLMNANPC1
SCHEMBL5443447 0.78 EPHX1 (0.48) HPGDALDH1A1MAPTLMNANPC1
SCHEMBL239451 0.78 HPGD (0.44) HPGDALDH1A1MAPTLMNANPC1
SCHEMBL11534684 0.77 EPHX1 (0.35) HPGDALDH1A1MAPTLMNANPC1
SCHEMBL604854 0.76
SCHEMBL17024295 0.74
SCHEMBL11513838 0.74 HPGD (0.41) HPGDALDH1A1MAPTLMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260557-B1 ASYMMETRIC 1:2 METAL COMPLEX DYESTUFS BAYER AG (DE) 1991-11-27 EP disclosed
EP-0260557-A2 Asymmetric 1:2 metal complex dyestufs BAYER AG (DE) 1988-03-23 EP disclosed