SCHEMBL11534684

SCHEMBL11534684

CCCCS(=O)(=O)NNC(=O)NNS(=O)(=O)CCCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 4/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPT P10636 3/20 0.35
LMNA P02545 2/20 0.35
HPGD P15428 2/20 0.35
MAPK1 P28482 2/20 0.35
NPC1 O15118 1/20 0.35
S1PR2 O95136 1/20 0.35
S1PR4 O95977 1/20 0.35
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35
XBP1 P17861 1/20 0.35
S1PR1 P21453 1/20 0.35
AGTR1 P30556 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11534020 0.92 FAAH (0.43) EPHX1ALDH1A1MAPTLMNAMAPK1
SCHEMBL11536215 0.86 KDM4E (0.31) ALDH1A1MAPTHPGDHSD17B10KDM4E
SCHEMBL10616576 0.81 HPGD (0.44) ALDH1A1MAPTLMNAHPGDMAPK1
SCHEMBL11543489 0.79 HPGD (0.33) LMNAHPGD
SCHEMBL11883209 0.78 RELA (0.39) ALDH1A1MAPTLMNAMAPK1MEN1
SCHEMBL9765230 0.77 HPGD (0.41) ALDH1A1MAPTLMNAHPGDMAPK1
SCHEMBL29142721 0.76 ALDH1A1 (0.41) ALDH1A1MAPTLMNAMAPK1SMN1; SMN2
SCHEMBL4565920 0.74 FAAH (0.50) HPGDKDM4E
SCHEMBL10778738 0.73 HPGD (0.38) ALDH1A1MAPTLMNAHPGDMAPK1
SCHEMBL19630951 0.72 HPGD (0.35) EPHX1ALDH1A1MAPTLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4133832-A Blowing agents -bis(hydrocarbylsulfonyl) carbohydrazides UNIROYAL, INC. (US) 1979-01-09 US disclosed
US-4096100-A Blowing agents-bis(hydrocarbylsulfonyl) carbohydrazides UNIROYAL, INC. (US) 1978-06-20 US disclosed