Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 4/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765425 | 1.00 | KCNE1 (0.47) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL9765413 | 1.00 | KCNE1 (0.47) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL8090416 | 0.82 | KDM4E (0.56) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL8090417 | 0.82 | KDM4E (0.56) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL8090414 | 0.82 | KDM4E (0.56) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL9766973 | 0.81 | KCNE1 (0.47) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL9766976 | 0.81 | KCNE1 (0.47) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL9766981 | 0.81 | KCNE1 (0.47) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL9209930 | 0.77 | KDM4E (0.44) | KCNE1KCNQ1ABCB1KDM4EABCC9 | |
| SCHEMBL9765458 | 0.77 | ABCB1 (0.43) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988723-A | Hypotensive agents, vasodilation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0344747-A1 | Benzopyran derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-06 | — | — | EP | disclosed |