Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872788 | 0.86 | HPRT1 (0.52) | TSHRCYP2A6HTR1BALDH1A1HTR1D | |
| SCHEMBL21122175 | 0.86 | HPRT1 (0.52) | TSHRCYP2A6HTR1BALDH1A1HTR1D | |
| SCHEMBL45343 | 0.82 | HTR1B (0.61) | TSHRHTR1BALDH1A1KDM4EHPGD | |
| SCHEMBL9765521 | 0.81 | MAPT (0.54) | CYP2A6ALDH1A1KDM4EHPGD | |
| SCHEMBL27808490 | 0.81 | HTR1B (0.59) | TSHRHTR1BALDH1A1KDM4EHPGD | |
| SCHEMBL27464937 | 0.81 | HTR1B (0.59) | TSHRHTR1BALDH1A1KDM4EHPGD | |
| SCHEMBL27808344 | 0.81 | HTR1B (0.59) | TSHRHTR1BALDH1A1KDM4EHPGD | |
| SCHEMBL27808393 | 0.81 | HTR1B (0.59) | TSHRHTR1BALDH1A1KDM4EHPGD | |
| SCHEMBL3818341 | 0.78 | ALDH1A1 (0.54) | TSHRCYP2A6HTR1BALDH1A1KDM4E | |
| SCHEMBL30503999 | 0.78 | ALDH1A1 (0.54) | TSHRCYP2A6HTR1BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272621-B1 | Method for the production of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF Aktiengesellschaft (DE) | 1991-11-27 | — | — | EP | disclosed |
| US-4845302-A | Preparation of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF AKTIENGSELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| EP-0272621-A2 | Method for the production of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF Aktiengesellschaft (DE) | 1988-06-29 | — | — | EP | disclosed |