SCHEMBL9872788

SCHEMBL9872788

CCOc1cccc2c1ccc1ccccc12

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.52
HTR1B P28222 9/20 0.50
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
HTR1D P28221 2/20 0.49
SLC6A4 P31645 1/20 0.47
HRH1 P35367 1/20 0.47
ALOX5 P09917 1/20 0.47
CYP2A6 P11509 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21122175 1.00 HPRT1 (0.52) HPRT1HTR1BALDH1A1TSHRHTR1D
SCHEMBL45343 0.88 HTR1B (0.61) HTR1BALDH1A1TSHRHTR1DSLC6A4
SCHEMBL10484241 0.87 HPRT1 (0.50) HPRT1ALDH1A1TSHRALOX5CYP2A6
SCHEMBL27464937 0.86 HTR1B (0.59) HTR1BALDH1A1TSHRHTR1DSLC6A4
SCHEMBL27808490 0.86 HTR1B (0.59) HTR1BALDH1A1TSHRHTR1DSLC6A4
SCHEMBL27808344 0.86 HTR1B (0.59) HTR1BALDH1A1TSHRHTR1DSLC6A4
SCHEMBL27808393 0.86 HTR1B (0.59) HTR1BALDH1A1TSHRHTR1DSLC6A4
SCHEMBL9765543 0.86 TSHR (0.49) HTR1BALDH1A1TSHRHTR1DCYP2A6
SCHEMBL10631451 0.86 TSHR (0.46) HPRT1HTR1BTSHRHTR1DSLC6A4
SCHEMBL10629369 0.86 CNR1 (0.58) HTR1BHTR1DSLC6A4HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4773916-A SPARK IGNITION WITH FUSED RING COMPOUNDS UNION OIL COMPANY OF CALIFORNIA (US) 1988-09-27 US claimed
WO-2024006827-A1 METHODS AND SYSTEMS FOR LIGHT-CONTROLLED SURFACE PATTERNING USING PHOTOMASKS 10X GENOMICS, INC. (US) 2024-01-04 WO disclosed
WO-2024006798-A1 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10X GENOMICS, INC. (US) 2024-01-04 WO disclosed
WO-2021065796-A1 CURABLE COMPOSITION, CURED MATERIAL, AND METHOD FOR FORMING CURED MATERIAL 東京応化工業株式会社 2021-04-08 WO disclosed
US-5024743-A Prophylaxis and therapy of infectious diseases MADAUS GMBH & CO. (DE) 1991-06-18 US disclosed
US-4835178-A Methylendioxyphenathrene and stilben derivatives, process for the preparation thereof, pharmaceutical compositions using these, and therapeutic applications DR. MADAUS & CO. (DE) 1989-05-30 US disclosed
US-4773916-A SPARK IGNITION WITH FUSED RING COMPOUNDS UNION OIL COMPANY OF CALIFORNIA (US) 1988-09-27 US disclosed