SCHEMBL9765555

SCHEMBL9765555

O=C(OCCN1CCCC1)c1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.47
GLA P06280 1/20 0.44
CYP3A4 P08684 1/20 0.44
HTR4 Q13639 1/20 0.44
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
SIGMAR1 Q99720 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9765530 0.92 TSHR (0.42) TSHR
SCHEMBL9765503 0.82 GAA (0.43)
SCHEMBL9765518 0.80 GRM7 (0.38)
SCHEMBL9765533 0.79
SCHEMBL9765504 0.79 PPOX (0.41) CYP1A2
SCHEMBL9765507 0.79 SLC6A2 (0.39)
SCHEMBL9765515 0.78 CHRM5 (0.43)
SCHEMBL29077269 0.78 MAPT (0.41) HPGD
SCHEMBL31154531 0.78 ALDH1A1 (0.47)
SCHEMBL9765544 0.77 GRM7 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034048-A Plant growth regulators, 5(tetrahydrophthalamido)benzoic acid derivatives for controlling weeds CIBA-GEIGY CORPORATION (US) 1991-07-23 US disclosed
US-4917721-A TETRAHYDROPHTHALIMIDO BENZOIC ACID THIOESTERS CIBA-GEIGY CORPORATION (US) 1990-04-17 US disclosed