Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363171 | 0.77 | — | — | |
| SCHEMBL9747862 | 0.68 | POLB (0.32) | POLB | |
| SCHEMBL10430717 | 0.67 | ALDH1A1 (0.58) | POLB | |
| SCHEMBL8593915 | 0.63 | TDP1 (0.44) | TDP2 | |
| SCHEMBL7761107 | 0.63 | TDP1 (0.63) | — | |
| SCHEMBL8621204 | 0.63 | TDP1 (0.67) | — | |
| SCHEMBL10430715 | 0.63 | ALDH1A1 (0.56) | — | |
| SCHEMBL9178035 | 0.63 | ALDH1A1 (0.47) | — | |
| SCHEMBL27794715 | 0.61 | ALDH1A1 (0.33) | TDP2 | |
| SCHEMBL25237284 | 0.61 | MEN1 (0.39) | TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988717-A | Optically active 1,4-dihydropyridine esters useful for treating circulatory illnesses | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4849433-A | The compound, (⃡)1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-pyridine-3,5-dicarboxylic acid, methyl isobutyl ester, compositions containing same and a method for effecting coronary dilation | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-18 | — | — | US | disclosed |
| US-4510310-A | 1,4-Dihydro-2,6-dimethyl-4-(2'-chlorophenyl)-3,5-dicarboxylic acid,methyl or ethyl,trifluoroethyl ester | BAYER AKTIENGESELLSCHAFT (DE) | 1985-04-09 | — | — | US | disclosed |