SCHEMBL7761107

SCHEMBL7761107

N#CCCOC(=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.63
LMNA P02545 2/20 0.59
MAPK1 P28482 1/20 0.52
HIF1A Q16665 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A3 Q01959 1/20 0.52
KMT2A Q03164 1/20 0.52
ALDH1A1 P00352 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
TSHR P16473 1/20 0.47
F2 P00734 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
KDM4E B2RXH2 1/20 0.45
GAA P10253 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4530882 0.89 TDP1 (0.70) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL17396777 0.88 TDP1 (0.73) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL17396705 0.86 TDP1 (0.71) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL8593915 0.85 TDP1 (0.44) TDP1LMNAMAPK1SLC6A2KMT2A
SCHEMBL5344554 0.84 TDP1 (0.53) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL14399299 0.84 TDP1 (0.53) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL10430717 0.83 ALDH1A1 (0.58) TDP1LMNAMAPK1HIF1AKMT2A
SCHEMBL6384961 0.83 TDP1 (0.66) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL907316 0.82 TDP1 (0.59) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL5857836 0.82 ESR1 (0.42) TDP1LMNAMAPK1SLC6A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4297103-A Process for the continuous one-bath dyeing of pile fabrics made of polyacrylonitrile/cotton BAYER AKTIENGESELLSCHAFT (DE) 1981-10-27 US claimed
US-20250287942-A1 FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-09-18 US disclosed
WO-2023205458-A2 FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-26 WO disclosed
EP-0688431-B1 METHOD FOR SCREENING CATALYTIC NON-ENZYME POLYPEPTIDES AND PROTEINS YEDA RES & DEV (IL) 2001-04-18 EP disclosed
US-5766861-A Method for screening catalytic non-enzyme polypeptides and proteins YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) 1998-06-16 US disclosed
EP-0688431-A4 METHOD FOR SCREENING CATALYTIC NON-ENZYME POLYPEPTIDES AND PROTEINS YEDA RES & DEV (IL) 1998-03-18 EP disclosed
EP-0688431-A1 METHOD FOR SCREENING CATALYTIC NON-ENZYME POLYPEPTIDES AND PROTEINS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1995-12-27 EP disclosed
WO-1994016332-A1 METHOD FOR SCREENING CATALYTIC NON-ENZYME POLYPEPTIDES AND PROTEINS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1994-07-21 WO disclosed
US-4297103-A Process for the continuous one-bath dyeing of pile fabrics made of polyacrylonitrile/cotton BAYER AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250287942-A1 FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS ACHE, BCHE, DDT TDP1 2245/4885LMNA 3388/4885MAPK1 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.