Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193205 | 0.80 | L3MBTL1 (0.59) | KMT2AMEN1ABCB1MAPTTSHR | |
| SCHEMBL7234199 | 0.78 | TBXA2R (0.48) | KMT2AMEN1ABCB1MAPTTSHR | |
| SCHEMBL7234206 | 0.78 | TBXA2R (0.48) | KMT2AMEN1ABCB1MAPTTSHR | |
| SCHEMBL7226193 | 0.77 | TSHR (0.45) | KMT2AMEN1MAPTTSHRLMNA | |
| SCHEMBL7226815 | 0.76 | TDP1 (0.44) | KMT2AMEN1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL20049934 | 0.75 | KMT2A (0.56) | KMT2AMEN1OPRM1OPRD1ABCB1 | |
| SCHEMBL10379764 | 0.75 | L3MBTL1 (0.62) | KMT2AMEN1ABCB1MAPTHTT | |
| SCHEMBL7226616 | 0.75 | NPC1 (0.46) | KMT2AMEN1ABCB1MAPTSMN1; SMN2 | |
| SCHEMBL7224862 | 0.75 | NPC1 (0.46) | KMT2AMEN1ABCB1MAPTSMN1; SMN2 | |
| SCHEMBL28808609 | 0.74 | LMNA (0.52) | KMT2AMEN1OPRM1OPRD1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435902-A1 | 2-HYDROXY-3-PHENOXY-PROPYL-SUBSTITUTED PIPERAZINES AND HOMOPIPERAZINES, THEIR MANUFACTURE AND USE. | BASF AG (DE) | 1991-07-10 | — | — | EP | disclosed |