Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679554 | 0.88 | HPGD (0.43) | SMN1; SMN2MAPTALDH1A1HPGDLMNA | |
| SCHEMBL18862666 | 0.81 | CYP3A4 (0.60) | SMN1; SMN2MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL10066481 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL1888745 | 0.81 | MEN1 (0.50) | ALDH1A1HPGDLMNAHSD17B10TYR | |
| SCHEMBL13460970 | 0.81 | ACHE (0.41) | MAPTALDH1A1LMNATDP1L3MBTL1 | |
| SCHEMBL22461066 | 0.80 | AR (0.38) | SMN1; SMN2MAPTALDH1A1HPGDLMNA | |
| SCHEMBL2229162 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2MAPTALDH1A1MAPK1RAB9A | |
| SCHEMBL1892567 | 0.79 | ALDH1A1 (0.41) | MAPTALDH1A1MAPK1RAB9ALMNA | |
| SCHEMBL16585297 | 0.79 | PPARA (0.38) | MAOB | |
| SCHEMBL987495 | 0.79 | PPARA (0.53) | SMN1; SMN2MAPTALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |