Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TYMP | P19971 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | TPO | P07202 | 1/20 | 0.40 |
| ▸ | LPO | P22079 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | UNG | P13051 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775601 | 0.75 | GPR84 (0.72) | GPR84SMN1; SMN2TSHRHSD17B10L3MBTL1 | |
| SCHEMBL1945397 | 0.74 | GPR84 (0.53) | GPR84SMN1; SMN2TSHRTYMPHSD17B10 | |
| SCHEMBL10130747 | 0.73 | GPR84 (0.50) | GPR84SMN1; SMN2TSHRTYMPHSD17B10 | |
| SCHEMBL1272345 | 0.71 | GPR84 (0.56) | GPR84SMN1; SMN2TSHRTYMPHSD17B10 | |
| SCHEMBL1702031 | 0.70 | GPR84 (0.96) | GPR84MAPTKMT2A | |
| SCHEMBL2959182 | 0.70 | GPR84 (0.50) | GPR84SMN1; SMN2TSHRTYMPHSD17B10 | |
| SCHEMBL3607183 | 0.69 | RAB9A (0.47) | GPR84SMN1; SMN2TSHRTYMPHSD17B10 | |
| SCHEMBL20599921 | 0.68 | SMN1; SMN2 (0.57) | GPR84SMN1; SMN2TSHRTYMPHSD17B10 | |
| SCHEMBL12775736 | 0.67 | GPR84 (0.56) | GPR84SMN1; SMN2TSHRTYMPHSD17B10 | |
| SCHEMBL27412187 | 0.67 | GPR84 (0.66) | GPR84SMN1; SMN2TSHRHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383868-A4 | 1,3-UNSYMMETRICAL STRAIGHT CHAIN ALKYL-SUBSTITUTED 8-PHENYLXANTHINES | — | 1991-12-04 | — | — | EP | disclosed |
| EP-0383868-A1 | 1,3-UNSYMMETRICAL STRAIGHT CHAIN ALKYL-SUBSTITUTED 8-PHENYLXANTHINES | MARION LABORATORIES, INC. (US) | 1990-08-29 | — | — | EP | disclosed |
| WO-1990000056-A1 | 1,3-UNSYMMETRICAL STRAIGHT CHAIN ALKYL-SUBSTITUTED 8-PHENYLXANTHINES | MARION LABORATORIES, INC. (US) | 1990-01-11 | — | — | WO | disclosed |