Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673442 | 0.84 | ERN1 (0.38) | ERN1ALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL1994831 | 0.83 | TDP1 (0.41) | ALDH1A1CYP3A4ATMTDP1TSHR | |
| SCHEMBL27687149 | 0.79 | GRIN2D (0.50) | ERN1ALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL12725905 | 0.78 | ERN1 (0.49) | ERN1ALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL31413408 | 0.78 | ERN1 (0.37) | ERN1ALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL1592576 | 0.78 | ERN1 (0.37) | ERN1ALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL28854528 | 0.78 | ERN1 (0.37) | ERN1ALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL935587 | 0.73 | ALDH1A1 (0.43) | ALDH1A1CYP3A4MAPTATMTDP1 | |
| SCHEMBL4246480 | 0.73 | ALDH1A1 (0.48) | ALDH1A1CYP3A4MAPTALOX15HSD17B10 | |
| SCHEMBL4950175 | 0.73 | GRIN2D (0.39) | ALDH1A1KDM4EMAPTALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266512-B1 | METHOD FOR THE PRODUCTION OF BENZOIC ACID DERIVATIVES FLUORINATED ON THE NUCLEUS | BAYER AG (DE) | 1991-12-04 | — | — | EP | claimed |