Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12920089 | 0.76 | CDC25A (0.34) | CDC25ACDC25BPOLL | |
| SCHEMBL15392608 | 0.74 | CDC25A (0.33) | CDC25ACDC25BPOLL | |
| SCHEMBL9766198 | 0.74 | APP (0.42) | CDC25ACDC25BAPEX1POLL | |
| SCHEMBL16445736 | 0.68 | — | — | |
| SCHEMBL16446782 | 0.67 | ACHE (0.31) | ACHE | |
| SCHEMBL11832066 | 0.65 | — | — | |
| SCHEMBL17068358 | 0.65 | ALDH1A1 (0.46) | — | |
| SCHEMBL13483993 | 0.64 | CYP1A2 (0.36) | — | |
| SCHEMBL6204247 | 0.63 | KDM4E (0.43) | ACHE | |
| SCHEMBL6591316 | 0.61 | ATM (0.57) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064649-A | CEPHALOSPORIN DERIVATIVES | BEECHAM GROUP P.L.C. (GB) | 1991-11-12 | — | — | US | disclosed |
| EP-0359536-A2 | Cephalosporin compounds, process for their preparation and pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1990-03-21 | — | — | EP | disclosed |