⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648373 | 0.80 | — | — | |
| SCHEMBL27548955 | 0.78 | CHRNB2 (0.44) | — | |
| SCHEMBL25301950 | 0.77 | MAPK1 (0.34) | — | |
| SCHEMBL13235855 | 0.73 | — | — | |
| SCHEMBL22323276 | 0.70 | — | — | |
| SCHEMBL7495038 | 0.64 | — | — | |
| SCHEMBL18925960 | 0.64 | — | — | |
| SCHEMBL18216656 | 0.64 | — | — | |
| SCHEMBL7417349 | 0.64 | TSHR (0.46) | — | |
| SCHEMBL17627904 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102060857-A | Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them | PHARMACIA ITALIA SPA | 2011-05-18 | — | — | CN | claimed |
| CN-1447810-A | Bicyclic pyrazoles with kinase inhibitor activity, process for their preparation and pharmaceutical compositions containing them | PHARMACIA ITALIA SPA (IT) | 2003-10-08 | — | — | CN | claimed |
| CN-102060857-A | Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them | PHARMACIA ITALIA SPA | 2011-05-18 | — | — | CN | disclosed |
| CN-1447810-A | Bicyclic pyrazoles with kinase inhibitor activity, process for their preparation and pharmaceutical compositions containing them | PHARMACIA ITALIA SPA (IT) | 2003-10-08 | — | — | CN | disclosed |
| EP-0287603-A4 | SUNSCREEN COMPOSITIONS AND COMPOUNDS FOR USE THEREIN | — | 1991-12-27 | — | — | EP | disclosed |
| EP-0287603-A1 | SUNSCREEN COMPOSITIONS AND COMPOUNDS FOR USE THEREIN. | ICI AUSTRALIA OPERATIONS (AU) | 1988-10-26 | — | — | EP | disclosed |
| WO-1988002251-A1 | SUNSCREEN COMPOSITIONS AND COMPOUNDS FOR USE THEREIN | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1988-04-07 | — | — | WO | disclosed |