Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 12/20 | 0.65 |
| ▸ | DRD2 | P14416 | 3/20 | 0.63 |
| ▸ | HTR3A | P46098 | 3/20 | 0.63 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.63 |
| ▸ | HTR3B | O95264 | 2/20 | 0.63 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.63 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.63 |
| ▸ | HTR2A | P28223 | 2/20 | 0.63 |
| ▸ | HTR2C | P28335 | 2/20 | 0.63 |
| ▸ | DRD3 | P35462 | 2/20 | 0.63 |
| ▸ | HTR2B | P41595 | 2/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15650737 | 0.85 | HTR4 (0.83) | HTR4DRD2HTR3ACYP1A2ADRA2A | |
| SCHEMBL15651357 | 0.82 | HTR4 (0.71) | HTR4DRD2HTR3AHTR3EHTR3B | |
| SCHEMBL22022238 | 0.82 | HTR4 (0.71) | HTR4DRD2HTR3AHTR3EHTR3B | |
| SCHEMBL15650650 | 0.82 | HTR4 (0.71) | HTR4DRD2HTR3AHTR3EHTR3B | |
| Monodeethylated-Mcp SCHEMBL15585981 | 0.81 | HTR4 (0.70) | HTR4DRD2HTR3AHTR3EHTR3B | |
| SCHEMBL8041200 | 0.81 | HTR4 (0.78) | HTR4DRD4 | |
| SCHEMBL17069817 | 0.81 | HTR4 (0.65) | HTR4DRD2HTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL7301566 | 0.81 | RAB9A (0.67) | HTR4DRD2HTR3AHTR3EHTR3B | |
| SCHEMBL9766463 | 0.81 | HTR4 (0.69) | HTR4DRD2HTR3AHTR3EHTR3B | |
| SCHEMBL15650947 | 0.80 | HTR4 (0.68) | HTR4DRD2HTR3AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2022257-A | — | — | None | — | — | JP | disclosed |
| US-5010108-A | Treatment of gastrointestinal disorders | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 1991-04-23 | — | — | US | disclosed |
| JP-H0222257-A | N-CYCLOALKYLAMINOETHYLBENZAMIDE DERIVATIVE, ITS PRODUCTION AND PHARMACEUTICAL USE | POLI IND CHIM SPA | 1990-01-25 | — | — | JP | disclosed |
| EP-0333073-A2 | N-cycloalkylaminoethylbenzamide derivatives, their synthesis and pharmaceutical preparations | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |