SCHEMBL9766504

SCHEMBL9766504

CCC(Cl)=C(C)CC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.43
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38
TDP1 Q9NUW8 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
KDM4E B2RXH2 1/20 0.31
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
TSHR P16473 2/20 0.31
LMNA P02545 1/20 0.31
SLC15A2 Q16348 1/20 0.31
CTH P32929 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27313770 0.79 FFAR3 (0.47) FFAR3LDHASRRTDP1ALDH1A1
SCHEMBL28811398 0.76 FFAR3 (0.50) FFAR3LDHASRRTDP1ALDH1A1
SCHEMBL6647501 0.74 LDHA (0.57) FFAR3LDHASRRTDP1ALDH1A1
SCHEMBL6647502 0.74 LDHA (0.57) FFAR3LDHASRRTDP1ALDH1A1
Propionic Acid SCHEMBL27578196 0.72
SCHEMBL1300401 0.70 FFAR3 (0.43) FFAR3LDHASRRTDP1ALDH1A1
Propionic Acid SCHEMBL10630460 0.69 FFAR3 (0.67) FFAR3LDHASRRTDP1ALDH1A1
SCHEMBL3614641 0.69
Malonic Acid SCHEMBL28331528 0.69 ALDH1A1 (0.67) FFAR3LDHASRRTDP1ALDH1A1
SCHEMBL11802162 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021587-A Synthesis of N,3,4-trisubstituted-3-azoline-2-ones PETROLITE CORPORATION (US) 1991-06-04 US disclosed