Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | INMT | O95050 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14749921 | 0.87 | PIK3CD (0.35) | GAAL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL17517145 | 0.87 | PIK3CD (0.35) | GAAL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL28354691 | 0.76 | TSHR (0.32) | ALDH1A1TSHRHTT | |
| SCHEMBL13036914 | 0.76 | BRD4 (0.35) | ALDH1A1 | |
| SCHEMBL1527372 | 0.74 | CYP3A4 (0.39) | GAAL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL13156797 | 0.74 | ENO1 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1527371 | 0.74 | CYP3A4 (0.39) | GAAL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL13434939 | 0.74 | DPP4 (0.31) | ALDH1A1 | |
| SCHEMBL14025940 | 0.74 | PER2 (0.40) | GAAL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL4704959 | 0.74 | CYP3A4 (0.39) | GAAL3MBTL1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003082-A | Reacting a lactam with hydrogen sulfide in the presence of an inorganic catalyst | PHILLIPS PETROLEUM COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4990628-A | Reacting lactam with hydrogen sulfide in presence of group 8 metals or compounds on alumina; support; sulfiding | PHILLIPS PETROLEUM COMPANY (US) | 1991-02-05 | — | — | US | disclosed |
| US-4956476-A | Catalytic reaction of a lactam with hydrogen sulfide to produce a thiolactam, alumina is the catalyst | PHILLIPS PETROLEUM COMPANY (US) | 1990-09-11 | — | — | US | disclosed |
| US-4145352-A | SULFACTIVE CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1979-03-20 | — | — | US | disclosed |