Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347113 | 1.00 | SIGMAR1 (0.55) | SIGMAR1MAOACHRM2EPHX2HDAC3 | |
| Hydrochloric Acid SCHEMBL28119181 | 0.98 | SIGMAR1 (0.53) | SIGMAR1MAOACHRM2EPHX2HDAC3 | |
| SCHEMBL2936967 | 0.98 | SIGMAR1 (0.56) | SIGMAR1MAOACHRM2EPHX2HDAC3 | |
| SCHEMBL11129280 | 0.92 | HDAC3 (0.51) | SIGMAR1MAOACHRM2EPHX2HDAC3 | |
| SCHEMBL30454697 | 0.89 | SIGMAR1 (0.51) | SIGMAR1MAOACHRM2EPHX2HDAC3 | |
| SCHEMBL2893366 | 0.84 | MEN1 (0.50) | SIGMAR1MAOACHRM2HDAC3HDAC8 | |
| SCHEMBL2889761 | 0.82 | MAOA (0.80) | SIGMAR1MAOACHRM2HRH4HRH3 | |
| SCHEMBL5950191 | 0.82 | MAOA (0.80) | SIGMAR1MAOACHRM2HRH4HRH3 | |
| SCHEMBL253468 | 0.82 | MAOA (0.80) | SIGMAR1MAOACHRM2HRH4HRH3 | |
| SCHEMBL2748121 | 0.82 | MAOA (0.80) | SIGMAR1MAOACHRM2HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4995997-A | Containing aromatic amine | YUSHIRO CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-02-26 | — | — | US | disclosed |
| EP-0388320-A1 | Antibacterial water-soluble cutting fluids resistant to yeast-like fungi | YUSHIRO CHEMICAL INDUSTRY CO. LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |