Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766727 | 1.00 | RAB9A (0.39) | RAB9AHRH3CYP2C9CRBNHTR1A | |
| SCHEMBL9160786 | 0.98 | RAB9A (0.35) | RAB9AHRH3CYP2C9HTR1ADRD2 | |
| SCHEMBL9160793 | 0.98 | RAB9A (0.35) | RAB9AHRH3CYP2C9HTR1ADRD2 | |
| SCHEMBL9160838 | 0.98 | RAB9A (0.40) | RAB9AHRH3CYP2C9CRBNHTR1A | |
| SCHEMBL9160827 | 0.98 | RAB9A (0.40) | RAB9AHRH3CYP2C9CRBNHTR1A | |
| SCHEMBL9157090 | 0.96 | RAB9A (0.39) | RAB9AHRH3CYP2C9CRBNHTR1A | |
| SCHEMBL9157082 | 0.96 | RAB9A (0.39) | RAB9AHRH3CYP2C9CRBNHTR1A | |
| SCHEMBL9158285 | 0.95 | RAB9A (0.38) | RAB9AHRH3CYP2C9CRBNHTR1A | |
| SCHEMBL9766631 | 0.95 | RAB9A (0.38) | RAB9AHRH3CYP2C9CRBNHTR1A | |
| SCHEMBL9158289 | 0.95 | RAB9A (0.38) | RAB9AHRH3CYP2C9CRBNHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |