Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194395 | 0.85 | PTPN1 (0.33) | KMT2AALDH1A1 | |
| SCHEMBL9766682 | 0.82 | HIF1A (0.38) | — | |
| SCHEMBL9766749 | 0.81 | HIF1A (0.44) | KMT2A | |
| SCHEMBL5358324 | 0.80 | DAO (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8194399 | 0.77 | HCAR2 (0.32) | — | |
| SCHEMBL9747880 | 0.75 | — | — | |
| SCHEMBL9766805 | 0.71 | GRIA1 (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL16510896 | 0.67 | KDM4E (0.35) | KMT2AALDH1A1POLB | |
| SCHEMBL15971797 | 0.66 | HCAR2 (0.34) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9735543 | 0.65 | IGF1R (0.37) | KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015478-A | Treatment of cancer with porphycene | CYTOPHARM, INC. (US) | 1991-05-14 | — | — | US | disclosed |
| US-4913907-A | LIPOSOMES | CYTOPHARM, INC. (US) | 1990-04-03 | — | — | US | disclosed |