Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 13/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766716 | 0.98 | HIF1A (0.46) | HIF1AEPAS1GPR84HCAR2KMT2A | |
| SCHEMBL9766682 | 0.95 | HIF1A (0.38) | HIF1AEPAS1GPR84HCAR2TYR | |
| SCHEMBL8194395 | 0.87 | PTPN1 (0.33) | HIF1AEPAS1GPR84HCAR2KMT2A | |
| SCHEMBL16328684 | 0.81 | NPC1 (0.43) | HIF1AEPAS1GPR84KMT2AMEN1 | |
| SCHEMBL9766756 | 0.81 | GRIN2D (0.37) | KMT2A | |
| SCHEMBL16328805 | 0.79 | HIF1A (0.44) | HIF1AEPAS1GPR84HCAR2KMT2A | |
| SCHEMBL16328687 | 0.79 | KDM4E (0.44) | HIF1AEPAS1GPR84HCAR2MAPT | |
| SCHEMBL16328776 | 0.77 | ALDH1A1 (0.42) | GPR84MAPTTDP1 | |
| SCHEMBL8194399 | 0.75 | HCAR2 (0.32) | HCAR2 | |
| SCHEMBL7086196 | 0.71 | GPR84 (0.45) | HIF1AEPAS1GPR84KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015478-A | Treatment of cancer with porphycene | CYTOPHARM, INC. (US) | 1991-05-14 | — | — | US | disclosed |
| US-4913907-A | LIPOSOMES | CYTOPHARM, INC. (US) | 1990-04-03 | — | — | US | disclosed |