Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766749 | 0.95 | HIF1A (0.44) | HIF1AEPAS1HCAR2TYRGPR84 | |
| SCHEMBL9766716 | 0.93 | HIF1A (0.46) | HIF1AEPAS1HCAR2TYRGPR84 | |
| SCHEMBL8194395 | 0.89 | PTPN1 (0.33) | HIF1AEPAS1HCAR2FFAR3KDM4E | |
| SCHEMBL16328684 | 0.86 | NPC1 (0.43) | HIF1AEPAS1GPR84 | |
| SCHEMBL16328805 | 0.84 | HIF1A (0.44) | HIF1AEPAS1HCAR2FFAR3HCAR3 | |
| SCHEMBL16328687 | 0.84 | KDM4E (0.44) | HIF1AEPAS1HCAR2FFAR3HCAR3 | |
| SCHEMBL9766756 | 0.82 | GRIN2D (0.37) | — | |
| SCHEMBL16328776 | 0.81 | ALDH1A1 (0.42) | KDM4EPKMGPR84 | |
| SCHEMBL8194399 | 0.76 | HCAR2 (0.32) | HCAR2DAO | |
| SCHEMBL13103031 | 0.75 | HIF1A (0.37) | HIF1AEPAS1GPR84DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015478-A | Treatment of cancer with porphycene | CYTOPHARM, INC. (US) | 1991-05-14 | — | — | US | disclosed |
| US-4913907-A | LIPOSOMES | CYTOPHARM, INC. (US) | 1990-04-03 | — | — | US | disclosed |