Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.37 |
| ▸ | CES1 | P23141 | 6/20 | 0.37 |
| ▸ | CES2 | O00748 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDCD4 | Q53EL6 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767002 | 0.85 | GPR84 (0.42) | PDCD4 | |
| SCHEMBL9767030 | 0.85 | PDCD4 (0.39) | PDCD4 | |
| SCHEMBL9767329 | 0.79 | PDCD4 (0.39) | PDCD4 | |
| SCHEMBL9326982 | 0.79 | PDCD4 (0.39) | PDCD4 | |
| SCHEMBL9766912 | 0.77 | PDCD4 (0.39) | PDCD4 | |
| SCHEMBL7296014 | 0.76 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL9422969 | 0.74 | PDCD4 (0.42) | PDCD4 | |
| SCHEMBL9746833 | 0.74 | PDCD4 (0.40) | PDCD4 | |
| SCHEMBL9744998 | 0.74 | PDCD4 (0.40) | PDCD4 | |
| SCHEMBL9745250 | 0.72 | PDCD4 (0.41) | PDCD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013850-A | 4-ethyl and 4-ethenyl-5-hydroxy-2(5H)-furanones substituted on alpha carbon of the ethyl or ethenyl side chain with a long chain alkyl group and on the beta carbon with a polar group, as anti-inflammatory agents | ALLERGAN, INC. (US) | 1991-05-07 | — | — | US | disclosed |