Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17921822 | 0.68 | LTA4H (0.39) | HTTLTA4HTSHRLMNAMAOA | |
| Diphenylether SCHEMBL11249937 | 0.65 | LTA4H (0.92) | LTA4HTSHRGSTP1MAOAMAOB | |
| SCHEMBL12332681 | 0.65 | LTA4H (0.58) | LTA4HTSHRGSTP1KMT2AMAOA | |
| Diphenylether SCHEMBL9598183 | 0.64 | LTA4H (0.57) | LTA4HTSHRIDH1GSTP1MAOA | |
| Diphenylether SCHEMBL22801164 | 0.64 | LTA4H (0.57) | LTA4HTSHRIDH1GSTP1MAOA | |
| SCHEMBL9766990 | 0.64 | HTT (0.43) | HTTTSHR | |
| Diphenylether SCHEMBL8462019 | 0.63 | LTA4H (0.86) | LTA4HTSHRGSTP1KMT2AMAOA | |
| Diphenylether SCHEMBL8157951 | 0.63 | LTA4H (0.86) | LTA4HTSHRGSTP1KMT2AMAOA | |
| Diphenylether SCHEMBL11437632 | 0.63 | LTA4H (0.86) | LTA4HTSHRGSTP1KMT2AMAOA | |
| Diphenylether SCHEMBL9061108 | 0.62 | LTA4H (1.00) | LTA4HTSHRGSTP1KMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072006-A | Chemical intermeidate; hypotensive agents, muscle relaxants | RECHERCHE SYNTEX FRANCE S.A. (FR) | 1991-12-10 | — | — | US | disclosed |
| US-4997846-A | Smooth muscle relaxants, hypotensives | RESEARCHE SYNTEX FRANCE, S.A. (FR) | 1991-03-05 | — | — | US | disclosed |
| EP-0377966-A2 | Novel benzopyranylpyrrolinone derivatives | RECHERCHE SYNTEX FRANCE SA (FR) | 1990-07-18 | — | — | EP | disclosed |