SCHEMBL9767407

SCHEMBL9767407

CCCCc1ncc(CO)n1Cc1ccc(NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)O)cc1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9767626 1.00 AGTR1 (0.46) AGTR1
SCHEMBL9869151 0.84
SCHEMBL9767781 0.84
SCHEMBL583 0.80 AGTR1 (0.53) AGTR1
SCHEMBL5547472 0.74 AGTR1 (0.72) AGTR1
SCHEMBL7890351 0.71 AGTR1 (0.60) AGTR1
SCHEMBL9871423 0.71 AGTR1 (0.53) AGTR1
SCHEMBL9767564 0.71 AGTR1 (0.53) AGTR1
Formic Acid SCHEMBL27588918 0.70 AGTR1 (0.70) AGTR1
SCHEMBL9205029 0.70 AGTR1 (0.59) AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5045540-A Amide or urea compounds containing imidazole groups WARNER-LAMBERT CO. (US) 1991-09-03 US disclosed
US-5041552-A Treatment of hypertension, heart failure, glaucoma and hyperaldosteronism WARNER-LAMBERT COMPANY (US) 1991-08-20 US disclosed
US-4981773-A Method for stabilization of organic base substances against light FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed