Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767564 | 1.00 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9767781 | 0.87 | — | — | |
| SCHEMBL9869151 | 0.87 | — | — | |
| SCHEMBL9588531 | 0.82 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9767515 | 0.81 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9767531 | 0.81 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9767507 | 0.78 | AGTR2 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9767511 | 0.78 | AGTR2 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9767419 | 0.78 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9767427 | 0.78 | AGTR1 (0.54) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041552-A | Treatment of hypertension, heart failure, glaucoma and hyperaldosteronism | WARNER-LAMBERT COMPANY (US) | 1991-08-20 | — | — | US | disclosed |