Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 6/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 3/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5862306 | 0.95 | ANPEP (0.46) | ANPEPERAP1ERAP2TSHRCYP3A4 | |
| SCHEMBL913495 | 0.95 | ANPEP (0.46) | ANPEPERAP1ERAP2TSHRCYP3A4 | |
| SCHEMBL89565 | 0.87 | ANPEP (0.44) | ANPEPERAP1ERAP2TSHRCYP3A4 | |
| SCHEMBL9767580 | 0.87 | ANPEP (0.44) | ANPEPERAP1ERAP2TSHRCYP3A4 | |
| SCHEMBL9767570 | 0.87 | ANPEP (0.44) | ANPEPERAP1ERAP2TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL56452 | 0.85 | GMNN (0.44) | ANPEPERAP1ERAP2TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL56538 | 0.85 | GMNN (0.44) | ANPEPERAP1ERAP2TSHRCYP3A4 | |
| SCHEMBL24073071 | 0.83 | ANPEP (0.41) | ANPEPERAP1ERAP2TSHRCYP3A4 | |
| SCHEMBL29322854 | 0.83 | HSD17B10 (0.48) | ANPEPERAP1ERAP2TSHRCYP3A4 | |
| SCHEMBL29322842 | 0.82 | L3MBTL1 (0.39) | ANPEPERAP1ERAP2TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019647-A | Antigrowth and anticarconogenic hexapeptide | MERCK & CO., INC. (US) | 1991-05-28 | — | — | US | disclosed |