Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 4/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | PRNP | P04156 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364304 | 0.75 | NR4A2 (0.48) | FERMT2NR4A2CHRM2CHRM4CHRM5 | |
| Bidesethyl Chloroquine SCHEMBL6659403 | 0.72 | CHRM2 (0.71) | FERMT2NR4A2CHRM2CHRM4CHRM5 | |
| Bidesethyl Chloroquine SCHEMBL29625380 | 0.72 | CHRM2 (0.71) | FERMT2NR4A2CHRM2CHRM4CHRM5 | |
| Bidesethyl Chloroquine SCHEMBL17706108 | 0.72 | CHRM2 (0.71) | FERMT2NR4A2CHRM2CHRM4CHRM5 | |
| SCHEMBL902310 | 0.72 | FERMT2 (0.56) | FERMT2NR4A2CHRM2CHRM4CHRM5 | |
| SCHEMBL9542816 | 0.71 | FERMT2 (0.49) | FERMT2NR4A2CHRM2CHRM4CHRM5 | |
| SCHEMBL6661655 | 0.70 | FERMT2 (0.53) | FERMT2NR4A2CHRM2CHRM4CHRM5 | |
| SCHEMBL7896777 | 0.69 | NR4A2 (0.47) | FERMT2NR4A2CYP2D6SOS2CYP1A2 | |
| SCHEMBL4367045 | 0.69 | FERMT2 (0.56) | FERMT2NR4A2CHRM2CHRM4CHRM5 | |
| SCHEMBL4374931 | 0.67 | FERMT2 (0.52) | FERMT2NR4A2CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011183-A1 | INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS -1 INFECTIVITY IN HUMAN CELLS | US COMMERCE (US) | 1991-08-08 | — | — | WO | disclosed |