SCHEMBL9767962

SCHEMBL9767962

Cc1cccc(C)c1N1N=CCC1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
ALDH1A1 P00352 4/20 0.37
POLB P06746 1/20 0.37
HTR7 P34969 2/20 0.35
HCAR1 Q9BXC0 1/20 0.34
AADAT Q8N5Z0 1/20 0.34
DPP4 P27487 3/20 0.33
HTR2B P41595 2/20 0.33
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ADRA2A P08913 1/20 0.33
DRD4 P21917 1/20 0.33
HRH2 P25021 1/20 0.33
OPRK1 P41145 1/20 0.33
SLC6A3 Q01959 1/20 0.33
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.33
OPRM1 P35372 1/20 0.33
ANPEP P15144 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8513034 0.80 MAPT (0.47) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL15285861 0.78 MAPT (0.36) MEN1KMT2AALDH1A1AADATMAPT
SCHEMBL181548 0.71 MEN1 (0.47) MEN1KMT2AALDH1A1POLBMAPT
SCHEMBL9835361 0.67 HSD17B10 (0.45) MEN1KMT2AALDH1A1POLBAADAT
SCHEMBL8604318 0.67 HDAC4 (0.39) MEN1KMT2AALDH1A1MAPTOPRK1
SCHEMBL7490265 0.66 CHRNA7 (0.31) MEN1KMT2AALDH1A1POLBMAPT
SCHEMBL16283581 0.64 GAA (0.43) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL22430467 0.60 MEN1 (0.56) MEN1KMT2AALDH1A1L3MBTL1GAA
SCHEMBL30404908 0.60 KMT2A (0.46) MEN1KMT2AALDH1A1POLBHTR7
SCHEMBL11630037 0.60 KMT2A (0.46) MEN1KMT2AALDH1A1POLBHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412121-A1 AZO PIGMENT COMPOSITION HAVING IMPROVED PROCESS HEAT STABILITY AND DRIED INK TRANSPARENCY. HOECHST CELANESE CORP (US) 1991-02-13 EP disclosed
US-4968352-A Diaryl pigments with improved heat stability and transparency containing coupled mixed bis-diazotized diamines and acid-substituted aromatic amines HOECHST CELANESE CORPORATION (US) 1990-11-06 US disclosed
WO-1989010385-A1 AZO PIGMENT COMPOSITION HAVING IMPROVED PROCESS HEAT STABILITY AND DRIED INK TRANSPARENCY HOECHST CELANESE CORPORATION (US) 1989-11-02 WO disclosed