SCHEMBL181548

SCHEMBL181548

O=C1CC=NN1c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.47
KMT2A Q03164 8/20 0.47
GAA P10253 8/20 0.47
ALDH1A1 P00352 5/20 0.47
MAPT P10636 5/20 0.47
KDM4E B2RXH2 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 2/20 0.47
CHRM2 P08172 1/20 0.47
CHRM1 P11229 1/20 0.47
TSHR P16473 1/20 0.47
PTGS1 P23219 1/20 0.47
DRD3 P35462 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
POLB P06746 1/20 0.44
LOX P28300 2/20 0.43
SHMT2 P34897 1/20 0.43
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5159834 0.82 F2 (0.43) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL16283581 0.80 GAA (0.43) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL9527067 0.80 MEN1 (0.50) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL10618445 0.80 POLB (0.46) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL7492867 0.80 MAPT (0.45) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL157611 0.78 L3MBTL1 (0.53) MEN1KMT2AGAAMAPTKDM4E
SCHEMBL8600426 0.78 DDB1 (0.43) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL23295789 0.75 MGLL (0.50) KMT2AGAAALDH1A1MAPTKDM4E
SCHEMBL8604318 0.75 HDAC4 (0.39) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL11025070 0.74 LMNA (0.38) KMT2AGAAALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117396185-A Hair dyeing composition 威娜国际运营瑞士责任有限公司 2024-01-12 CN claimed
CN-114315803-A Synthesis method of red bisazo organic pigment 上海应用技术大学 2022-04-12 CN claimed
CN-113980001-A Pyrazole alcohol-pyridazinone coupling compound, pharmaceutical composition thereof and application thereof in medicines 贵州医科大学 2022-01-28 CN claimed
CN-101506214-A Pyrazoloquinazolinones as PARP inhibitors ABBOTT LAB (US) 2009-08-12 CN claimed
EP-1353636-A1 NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING P & G-Clairol, Inc. (US) 2003-10-22 EP claimed
WO-2002094208-A1 NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING P & G - CLAIROL, INC. (US) 2002-11-28 WO claimed
EP-0410654-B1 Light- sensitive composition FUJI PHOTO FILM CO LTD (JP) 1998-10-28 EP claimed
US-5424268-A Imaging medium and process POLAROID CORPORATION (US) 1995-06-13 US claimed
US-5064747-A Improved photosensitivity using an unsaturated 1,3-dithiol-2-ylidene derivative; lithographic printing plates; photoresists FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 US claimed
EP-0410654-A2 Light- sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1991-01-30 EP claimed
EP-0401797-A1 Active esters for solid phase peptide synthesis PerSeptive Biosystems, Inc. (US) 1990-12-12 EP claimed
US-4254220-A ENZYME INHIBITOR FOR GLUCOSE OXIDASE BUT NOT PEROXIDASE TO USE CHROMOGENS SCLAVO, S.P.A. (IT) 1981-03-03 US claimed
US-12628554-B2 Photoelectric conversion element, imaging element, optical sensor, and compound FUJIFILM CORPORATION (JP) 2026-05-12 US disclosed
US-12568754-B2 Laminate comprising a wavelength-conversion material and a wavelength-selective absorption layer, display device, and organic electroluminescent display device FUJIFILM CORPORATION (JP) 2026-03-03 US disclosed
US-20250393473-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, AND OPTICAL SENSOR FUJIFILM CORP (JP) 2025-12-25 US disclosed
US-20250374741-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORP (JP) 2025-12-04 US disclosed
US-3943142-A Dye intermediates and their preparation and use in the synthesis of methine dyes EASTMAN KODAK COMPANY (US) 1976-03-09 US disclosed
US-3936308-A Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed
US-3935182-A Water-soluble quaternary ammonium heterocyclic azo dyestuffs STERLING DRUG INC. (US) 1976-01-27 US disclosed
US-3935010-A IMIDAZOQUINOXALINE DESENSITIZER EASTMAN KODAK COMPANY (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12568754-B2 Laminate comprising a wavelength-conversion material and a wavelength-selective absorption layer, display device, and organic electroluminescent display device STRA6, CDH1, EPCAM MEN1 4530/4885KMT2A 1431/4885GAA 3463/4885
US-20250393473-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, AND OPTICAL SENSOR NR2E3, CRY1, CRY2 MEN1 1805/4885KMT2A 1830/4885GAA 4412/4885
US-12628554-B2 Photoelectric conversion element, imaging element, optical sensor, and compound SCO2, CRY2, PYM1 MEN1 890/4885KMT2A 2377/4885GAA 4773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.