SCHEMBL97680

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3443629	0.90	NPC1 (0.69)	NPC1RAB9ASMN1; SMN2RECQLPOLB
	SCHEMBL97634	0.87	POLB (0.68)	NPC1RAB9ASMN1; SMN2RECQLPOLB
	SCHEMBL9126580	0.85	ROCK2 (0.56)	NPC1RAB9ASMN1; SMN2RECQLPOLB
	SCHEMBL17346621	0.78	NPC1 (0.72)	NPC1RAB9ASMN1; SMN2RECQLTSHR
	SCHEMBL10596423	0.78	NPC1 (0.72)	NPC1RAB9ASMN1; SMN2RECQLTSHR
	SCHEMBL9150484	0.78	PKM (0.51)	NPC1RAB9ASMN1; SMN2RECQLPOLB
	SCHEMBL9080564	0.78	POLB (0.68)	NPC1RAB9ASMN1; SMN2RECQLPOLB
	SCHEMBL9126986	0.77	HPGD (0.56)	NPC1RAB9ASMN1; SMN2RECQLPOLB
	SCHEMBL335344	0.76	SMN1; SMN2 (0.52)	NPC1RAB9ASMN1; SMN2RECQLPOLB
	Phenethyl Phenylcarbamate SCHEMBL1835027	0.76	NPC1 (0.81)	NPC1RAB9ASMN1; SMN2RECQLPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.