Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.54 |
| ▸ | MTOR | P42345 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768061 | 0.84 | MAPT (0.57) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| SCHEMBL9768027 | 0.82 | ADRB2 (0.54) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| SCHEMBL9768222 | 0.79 | ADRB2 (0.61) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| SCHEMBL9767972 | 0.76 | ADRB2 (0.58) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| SCHEMBL19707580 | 0.76 | HTT (0.50) | ADRB2ADRB1TSHRADRB3CYP1A2 | |
| SCHEMBL9768050 | 0.75 | MAPT (0.56) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| SCHEMBL9768323 | 0.74 | MAPT (0.55) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| Epinephrine SCHEMBL20360472 | 0.73 | KDM4E (0.90) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| Isoproterenol SCHEMBL28106224 | 0.73 | MAPT (0.88) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| Racepinephrine SCHEMBL3815 | 0.71 | KDM4E (1.00) | MAPTTDP1ADRB2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047592-A | Selective hydrogenolysis process | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |