SCHEMBL9768092

SCHEMBL9768092

COc1ccc(NCC(=O)c2ccc(O)c(O)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.64
CA2 P00918 5/20 0.64
CA12 O43570 3/20 0.64
CA9 Q16790 3/20 0.64
ACHE P22303 1/20 0.53
ALPL P05186 3/20 0.51
ALPG P10696 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.50
NPC1 O15118 3/20 0.50
HPGD P15428 2/20 0.50
RAB9A P51151 2/20 0.50
ALDH1A1 P00352 1/20 0.50
AGTR1 P30556 1/20 0.50
POLB P06746 3/20 0.49
GAA P10253 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 1/20 0.49
JAK2 O60674 1/20 0.49
PTP4A3 O75365 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1180270 0.86 CA1 (0.76) CA1CA2CA12CA9ACHE
SCHEMBL9768193 0.84 CA12 (0.61) CA1CA2CA12CA9ALPL
SCHEMBL9768311 0.83 ERCC1 (0.51) CA1CA2CA12CA9ALPL
SCHEMBL1180707 0.81 CA12 (0.58) CA1CA2CA12CA9ACHE
SCHEMBL9768023 0.81 ALPL (0.51) CA1CA2CA12CA9ALPL
SCHEMBL9768107 0.81 ALPL (0.51) CA1CA2CA12CA9ALPL
SCHEMBL9768082 0.81 ALPL (0.51) CA1CA2CA12CA9ALPL
SCHEMBL9768260 0.80 ERCC1 (0.60) CA1CA2CA12CA9ALPL
SCHEMBL15033927 0.79 CA12 (0.67) CA1CA2CA12CA9ACHE
SCHEMBL9424289 0.79 NPC1 (0.68) CA1CA2CA12CA9ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5047592-A Selective hydrogenolysis process ETHYL CORPORATION (US) 1991-09-10 US disclosed