SCHEMBL9768193

SCHEMBL9768193

Cc1ccc(NCC(=O)c2ccc(O)c(O)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.61
CA1 P00915 5/20 0.61
CA2 P00918 5/20 0.61
CA9 Q16790 5/20 0.61
ALPG P10696 7/20 0.58
ALPL P05186 5/20 0.58
ALDH1A1 P00352 2/20 0.57
AGTR1 P30556 2/20 0.57
TOP1 P11387 1/20 0.47
PLAA Q9Y263 2/20 0.47
CCR5 P51681 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
HPGD P15428 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ERCC1 P07992 1/20 0.47
ERCC4 Q92889 1/20 0.47
ALPI P09923 1/20 0.46
CA7 P43166 2/20 0.45
CA14 Q9ULX7 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30444865 0.85 CA12 (0.73) CA12CA1CA2CA9ALDH1A1
SCHEMBL9768107 0.84 ALPL (0.51) CA12CA1CA2CA9ALPG
SCHEMBL9768082 0.84 ALPL (0.51) CA12CA1CA2CA9ALPG
SCHEMBL9768023 0.84 ALPL (0.51) CA12CA1CA2CA9ALPG
SCHEMBL9768260 0.84 ERCC1 (0.60) CA12CA1CA2CA9ALPG
SCHEMBL9768047 0.84 CA12 (0.55) CA12CA1CA2CA9ALPG
SCHEMBL9768092 0.84 CA1 (0.64) CA12CA1CA2CA9ALPG
SCHEMBL9768118 0.81 P2RX1 (0.49) CA12CA1CA2ALPGALPL
SCHEMBL9768311 0.79 ERCC1 (0.51) CA12CA1CA2CA9ALPG
SCHEMBL9768234 0.78 INSR (0.57) CA12CA1CA2CA9ALPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5047592-A Selective hydrogenolysis process ETHYL CORPORATION (US) 1991-09-10 US disclosed