Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383958 | 0.86 | TET2 (0.46) | TET2TET3TET1GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL28385647 | 0.84 | TET2 (0.45) | TET2TET3TET1GRIK1GRIK2 | |
| Trimethylammonium SCHEMBL2379186 | 0.75 | TET2 (0.31) | TET2 | |
| SCHEMBL1155350 | 0.75 | — | — | |
| Trimethylammonium SCHEMBL6424141 | 0.75 | TET2 (0.31) | TET2 | |
| Water SCHEMBL28400902 | 0.74 | — | — | |
| SCHEMBL1155348 | 0.72 | GSR (0.33) | — | |
| Trimethylammonium SCHEMBL69320 | 0.72 | FFAR3 (0.32) | — | |
| Trimethylammonium SCHEMBL1345929 | 0.72 | FFAR3 (0.32) | — | |
| SCHEMBL6931530 | 0.72 | TET2 (0.33) | TET2TET3TET1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068297-A | Polymers for dewatering sludge and wastes | NALCO CHEMICAL COMPANY (US) | 1991-11-26 | — | — | US | disclosed |