Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768202 | 1.00 | GAA (0.36) | GAAALDH1A1HTTRAPGEF4PDE2A | |
| SCHEMBL9218250 | 0.85 | GAA (0.33) | GAAALDH1A1HTTRAPGEF4PDE2A | |
| SCHEMBL9768313 | 0.79 | ALDH1A1 (0.33) | GAAALDH1A1HTTKMT2AKDM4E | |
| SCHEMBL9219630 | 0.78 | ABCB1 (0.33) | GAAALDH1A1HTTKMT2AMAPT | |
| SCHEMBL27286601 | 0.77 | GAA (0.39) | GAAALDH1A1HTTRAPGEF4PDE2A | |
| SCHEMBL9768157 | 0.77 | ALDH1A1 (0.37) | GAAALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL9768163 | 0.77 | ALDH1A1 (0.37) | GAAALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL7713546 | 0.75 | ALDH1A1 (0.38) | GAAALDH1A1HTTKMT2AMAPT | |
| SCHEMBL6258551 | 0.75 | RAPGEF3 (0.38) | GAAALDH1A1HTTRAPGEF4PDE2A | |
| SCHEMBL7713550 | 0.75 | ALDH1A1 (0.38) | GAAALDH1A1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064844-A | Miticides | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-11-12 | — | — | US | disclosed |