SCHEMBL9768305

SCHEMBL9768305

CCCCNCC(=O)c1ccc(O)c(O)c1Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.43
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
LMNA P02545 2/20 0.42
TSHR P16473 2/20 0.42
USP2 O75604 1/20 0.42
CA2 P00918 1/20 0.42
HPGD P15428 1/20 0.42
BLM P54132 1/20 0.42
SLC12A2 P55011 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GAA P10253 2/20 0.38
PTPN1 P18031 1/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
POLB P06746 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8153080 0.75 HDAC3 (0.61) HDAC3KDM4EALDH1A1NPSR1GAA
SCHEMBL9768329 0.74 ADRB2 (0.43) KDM4EALDH1A1LMNA
SCHEMBL2875428 0.70 CTNNB1 (0.53) KDM4EALDH1A1LMNATSHRCA2
SCHEMBL11310671 0.70 GAA (0.53) HDAC3KDM4EALDH1A1LMNATSHR
SCHEMBL11691248 0.69 NPC1 (0.49) KDM4EALDH1A1NPSR1TSHRUSP2
Hydrochloric Acid SCHEMBL11041256 0.69 GAA (0.51) HDAC3KDM4EALDH1A1LMNATSHR
SCHEMBL22069671 0.69 GAA (0.73) HDAC3KDM4EALDH1A1NPSR1LMNA
Bromide SCHEMBL11691358 0.68 NPC1 (0.48) KDM4EALDH1A1NPSR1TSHRUSP2
SCHEMBL11316982 0.68 NCEH1 (0.43) HDAC3TSHRHPGDGAAHTT
SCHEMBL1592900 0.68 PPARA (0.44) LMNAMAPTMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5047592-A Selective hydrogenolysis process ETHYL CORPORATION (US) 1991-09-10 US disclosed