SCHEMBL976845

SCHEMBL976845

CC(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
THRB P10828 1/20 0.54
FEN1 P39748 1/20 0.47
HPGD P15428 3/20 0.45
NPC1 O15118 2/20 0.45
GLA P06280 1/20 0.45
TSHR P16473 1/20 0.43
AKR1B1 P15121 1/20 0.43
POLB P06746 1/20 0.43
NOTUM Q6P988 2/20 0.42
TYK2 P29597 2/20 0.42
JAK2 O60674 1/20 0.42
CYP3A4 P08684 1/20 0.42
JAK1 P23458 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
RAB9A P51151 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
TAS1R2 Q8TE23 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13100052 0.86 ALDH1A1 (0.52) ALDH1A1THRBFEN1HPGDNPC1
SCHEMBL29593170 0.86 THRB (0.71) ALDH1A1THRBFEN1HPGDNPC1
SCHEMBL3785600 0.86 ALDH1A1 (0.52) ALDH1A1THRBFEN1HPGDNPC1
SCHEMBL1237641 0.86 THRB (0.71) ALDH1A1THRBFEN1HPGDNPC1
SCHEMBL1188823 0.84 ALDH1A1 (0.50) ALDH1A1THRBFEN1HPGDNPC1
SCHEMBL29443043 0.84 GAA (0.54) ALDH1A1POLBTYK2JAK2JAK1
SCHEMBL716550 0.84 GAA (0.54) ALDH1A1POLBTYK2JAK2JAK1
SCHEMBL8262560 0.84 ALDH1A1 (0.50) ALDH1A1THRBFEN1HPGDNPC1
SCHEMBL7286473 0.83 TSHR (0.59) ALDH1A1THRBFEN1HPGDTSHR
SCHEMBL24301693 0.81 CA9 (0.57) ALDH1A1THRBHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119842830-A Preparation method of (S) -1- (2, 6-dichlorophenyl) ethanol 上海泓博尚奕药物技术有限公司 2025-04-18 CN claimed
CN-119570755-A Ketone reductase mutant and application thereof in synthesis of (R) -1- (2, 6-dichlorophenyl) ethanol 上海泓博尚奕药物技术有限公司 2025-03-07 CN claimed
CN-119285435-A Recycling method of 2, 6-dichloro acetophenone 江苏优嘉植物保护有限公司 2025-01-10 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-115109759-B Carbonyl reductase LsCR mutant, engineering bacterium and application thereof in preparation of chiral alcohol by asymmetric reduction of carbonyl compound 浙江工业大学 2024-05-03 CN claimed
CN-111253233-B Transposition method of acetophenone isomer 浙江禾本科技股份有限公司 2023-02-28 CN claimed
CN-115109759-A Carbonyl reductase LsCR mutant, engineering bacteria and application in preparation of chiral alcohol by asymmetrically reducing carbonyl compound 浙江工业大学 2022-09-27 CN claimed
CN-113307721-B Recovery and utilization of 2, 4-dichloroacetophenone isomer 2, 6-dichloroacetophenone 浙江禾本科技股份有限公司 2022-04-26 CN claimed
CN-113307721-A Recovery and utilization of 2, 4-dichloroacetophenone isomer 2, 6-dichloroacetophenone 浙江禾本科技股份有限公司 2021-08-27 CN claimed
CN-108445121-B Method for separating and measuring 2, 4-dichloroacetophenone and 2, 6-dichloroacetophenone isomers by gas chromatography 常州市盛辉药业有限公司 2021-06-25 CN claimed
CN-112299974-A Method for synthesizing 2, 4-dichloroacetophenone by recycling acetophenone crystallization waste 宁夏瑞泰科技股份有限公司 2021-02-02 CN claimed
CN-111253233-A Transposition method of acetophenone isomer 浙江禾本科技股份有限公司 2020-06-09 CN claimed
CN-105254586-A Sulfur-containing heterocyclic chalcone derivatives, preparation method and applications UNIV ZHENGZHOU 2016-01-20 CN claimed
US-9174906-B2 Process for producing optically active secondary alcohol KANTO KAGAKU KABUSHIKI KAISHA (JP) 2015-11-03 US claimed
EP-4041727-B1 ATF6 MODULATORS AND USES THEREOF ALTOS LABS INC (US) 2026-05-20 EP disclosed
EP-3881048-B1 DEVICE FOR REMOVING VOLATILE ORGANIC COMPOUNDS LETAT FRANCAIS REPRESENTE PAR LE MINI DE LINTERIEUR (FR) 2026-05-06 EP disclosed
EP-0012850-B1 PROCESS FOR THE PREPARATION OF KETONES BY REACTING CARBOXYLIC-ACID HALIDES WITH ALKYL ALUMINIUM COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1981-11-25 EP disclosed
US-4282145-A Process for the preparation of azetidines GIST-BROCADES N.V. (NL) 1981-08-04 US disclosed
US-4266066-A FROM CARBOXYLIC ACYL HALIDE AND ALUMINUM ALKYL COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1981-05-05 US disclosed