Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.87 |
| ▸ | PGR | P06401 | 5/20 | 0.87 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.87 |
| ▸ | USP2 | O75604 | 3/20 | 0.87 |
| ▸ | MEN1 | O00255 | 1/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.87 |
| ▸ | LMNA | P02545 | 2/20 | 0.86 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.86 |
| ▸ | MAPT | P10636 | 2/20 | 0.86 |
| ▸ | MLNR | O43193 | 1/20 | 0.86 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.86 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.86 |
| ▸ | PPARG | P37231 | 1/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.86 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.86 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.85 |
| ▸ | DRD2 | P14416 | 1/20 | 0.85 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509816 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4USP2MEN1 | |
| SCHEMBL30721453 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4USP2MEN1 | |
| SCHEMBL11883718 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4USP2MEN1 | |
| SCHEMBL29395446 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4USP2MEN1 | |
| SCHEMBL9768474 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4USP2MEN1 | |
| SCHEMBL11883728 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4USP2MEN1 | |
| SCHEMBL25372269 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4USP2MEN1 | |
| SCHEMBL11050044 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4USP2MEN1 | |
| SCHEMBL122396 | 1.00 | NR3C1 (0.87) | NR3C1PGRCYP3A4USP2MEN1 | |
| SCHEMBL1943651 | 0.94 | NR3C1 (0.92) | NR3C1PGRCYP3A4USP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026693-A | Novel 9α-fluoro- or chloro-corticosteroid esters and a process for their preparation | HOVIONE INTER LTD. (CH) | 1991-06-25 | — | — | US | disclosed |
| US-4427591-A | TOPICAL ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1984-01-24 | — | — | US | disclosed |
| US-4336200-A | 17α-Acyloxy-5β-corticoids | THE UPJOHN COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4318853-A | ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| US-3984544-A | Retinoic acid esters of steroids of the pregnane series, their use in the treatment of acne and pharmaceutical formulations useful therefor | SCHERING CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |